Status:
ACTIVE_NOT_RECRUITING
Effects of Dextrose Prolotherapy in Patients With Knee Osteoarthritis
Lead Sponsor:
Istanbul University
Conditions:
Knee Osteoarthritis
Eligibility:
All Genders
40-65 years
Phase:
NA
Brief Summary
In this prospective, randomized, controlled, single-blinded study, we aimed to evaluate the effects of Dextrose Prolotherapy injections in patients with chronic knee osteoarthritis.
Detailed Description
Patients admitted to Istanbul University, Istanbul Faculty of Medicine, Department of Physical Medicine and Rehabilitation Outpatient Clinic with a diagnosis of knee osteoarthritis and who meet the in...
Eligibility Criteria
Inclusion
- Unilateral or bilateral symptomatic knee pain resistant to conservative treatment for at least three months
- Presence of Kellgren-Lawrence stage 2-3 osteoarthritis on current anterior-posterior knee radiographs
- 40-65 years of age
- Functional ambulation scale stage 4-5
Exclusion
- Kellgren-Lawrence stage 1 or stage 4 osteoarthritis on current anterior-posterior knee radiographs
- Intra-articular knee injection within the last six months
- History of severe trauma to the knee within the past six months
- Concomitant severe meniscus or ligament injury, surgery applied to the knee area
- Presence of severe effusion, inflammatory joint disease, infection, hematological and oncological disease in the knee.
- Having a bleeding disorder and / or using warfarin
- Patients with hemoglobin less than 11g/dL and platelet count of less than 150,000 platelets per microliter
- Presence of uncontrolled diabetes mellitus
- Presence of cardiac or systemic disease that may affect exercise
- The presence of neurological disease and psychiatric disease such as Parkinson's disease, stroke history that may affect balance
- Body Mass Index ≥35 kg/m²
- Allergy to local anesthetic
Key Trial Info
Start Date :
August 15 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 20 2024
Estimated Enrollment :
66 Patients enrolled
Trial Details
Trial ID
NCT06063356
Start Date
August 15 2023
End Date
June 20 2024
Last Update
January 9 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Istanbul University Istanbul Faculty of Medicine, Department of Physical Medicine and Rehabilitation
Istanbul, Turkey (Türkiye)