Status:

UNKNOWN

Respiratory Effects of Flow-Controlled Ventilation and Jet Ventilation in Patients Undergoing Laryngotracheal Surgery

Lead Sponsor:

University Hospital, Geneva

Conditions:

Ventilation

Lung Function

Eligibility:

All Genders

18-100 years

Phase:

NA

Brief Summary

Laryngotracheal surgery often requires a small diameter endotracheal tube to oxygenate patients under general anesthesia. Oxygenation is often only possible with high-frequency jet ventilators due to ...

Detailed Description

This study is a randomized, controlled, assessor blind, monocentric study. A new ventilation mode, called Flow Controlled Ventilation (FCV), has been suggested to minimize the amount of dissipated en...

Eligibility Criteria

Inclusion

  • Informed Consent signed by the subject
  • General anesthesia for laryngotracheal surgery
  • Adult patients, female and male, over 18 years of age
  • Elective surgery

Exclusion

  • Documented severe heart conditions (New York Heart Association Class 4, severe pulmonary hypertension)
  • Documented severe respiratory disease (uncontrolled asthma, severe pulmonary fibrosis, chronic obstructive pulmonary disease GOLD 4)
  • Documented severe Neurological diseases (Acute ischemic and hemorrhagic stroke within the preceding 3 months, uncontrolled seizures)
  • Surgery that requires tracheotomy
  • Obesity (Body Mass Index ≥ 30 kg/m2)
  • Inability to follow the procedures of the study (mental condition or language barrier e.g. incomprehension of French language)
  • Previous enrolment into the current study or other study that involves unknown medication in the past 12 months
  • Allergy or contraindication to Propofol and/or Remifentanil and/or Rocuronium

Key Trial Info

Start Date :

September 5 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT06063798

Start Date

September 5 2023

End Date

December 1 2025

Last Update

October 3 2023

Active Locations (1)

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1

Geneva University Hospitals

Geneva, Switzerland, 1211