Status:
COMPLETED
Evaluation of Perfusion Index Change Post Passive Leg Raising for Fluid Responsiveness in Critically Ill
Lead Sponsor:
National Hepatology & Tropical Medicine Research Institute
Conditions:
Fluid Responsiveness
Eligibility:
All Genders
18+ years
Brief Summary
Peripheral Perfusion Index (PI) has been investigated for its use in hemodynamic monitoring. The PI is derived from the photoelectric plethysmographic signal of the pulse oximeter. The changes in the ...
Detailed Description
After approval by NHTMRI-IRB Ethical Committee.All demographic data will be obtained including the patients age, sex,associated co-morbidities (diabetes mellitus \& hypertension). Continuous blood pr...
Eligibility Criteria
Inclusion
- The subjects are adults aged ≥18 years old
- admitted tothe intensive care unit of the National Hepatologyand Tropical Medicine Research Institute (NHTMRI).
- Patients with clinical signs of hemodynamic instability i.e. a systolic blood pressure \< 90 mmHg or decrease in systolic blood pressure \> 40 mmHg, signs of organ hypoperfusion as oliguria \< 0.5ml/Kg/hour.
Exclusion
- If there is known peripheral vascular disease
- or ≥ 2 vasopressors with the maximum doses
- or in the presence of nail polish as readings from pulse oximeter will be distortedin these cases
- or if there is contraindication for PLR as uncontrolled hemodynamic status
- intracranial hypertension
- severe chronic obstructive pulmonary disease
- broncho-alveolar fistula
- severe emphysema
- and those with pre-existing comorbidities including severe left and right ventricular dysfunction, severe pulmonary hypertension
- severe obesity (BMI \>40 kg/m2)
- pregnancy.
Key Trial Info
Start Date :
August 28 2023
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 18 2025
Estimated Enrollment :
91 Patients enrolled
Trial Details
Trial ID
NCT06063993
Start Date
August 28 2023
End Date
June 18 2025
Last Update
June 26 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
NHTMRI
Cairo, Egypt, 4260010