Status:

COMPLETED

Effect of Intravenous Lignocaine Infusion on Intraoperative End Tidal Desflurane Concentration Requirements

Lead Sponsor:

Universiti Kebangsaan Malaysia Medical Centre

Conditions:

Cholelithiases

Appendicitis

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

Lignocaine is a local anaesthetic that is widely used in all medical and surgical fields. Many clinical studies have shown that intravenous (IV) lignocaine given in the perioperative period was safe, ...

Detailed Description

All volunteers will be randomly assigned into two groups based on computer generated randomisation tables. Group Lignocaine will receive an IV bolus dose of 1.5 mg/kg of 2% lignocaine HCL diluted up ...

Eligibility Criteria

Inclusion

  • American Society of Anaesthesiology (ASA) I or II patients.
  • Patients aged between 18-75 years of age.
  • Patients scheduled for elective laparoscopic cholecystectomy.
  • Patients scheduled for laparoscopic hernioplasty.
  • Patients scheduled for emergency laparoscopic appendicectomy.
  • Patients scheduled for emergency laparoscopic cystectomy.
  • Patient weight ranging from 50 - 100 kg.
  • Surgery lasting at least one hour.

Exclusion

  • Patients with a known allergy to study drug.
  • Patients with body mass index (BMI) more than 35 kg m-2.
  • Patients who are taking sedatives.
  • Patients with chronic substance abuse.

Key Trial Info

Start Date :

January 21 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 19 2021

Estimated Enrollment :

48 Patients enrolled

Trial Details

Trial ID

NCT06064331

Start Date

January 21 2021

End Date

November 19 2021

Last Update

October 3 2023

Active Locations (1)

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Pusat Perubatan Universiti Kebangsaan Malaysia

Kuala Lumpur, Kuala Lumpur, Malaysia, 56000

Effect of Intravenous Lignocaine Infusion on Intraoperative End Tidal Desflurane Concentration Requirements | DecenTrialz