Status:

RECRUITING

An Organoid-based Functional Precision Medicine Trial in Osteosarcoma

Lead Sponsor:

Jonsson Comprehensive Cancer Center

Conditions:

Osteosarcoma

Eligibility:

All Genders

Brief Summary

The purpose of this study is to examine if we can predict sensitivity of osteosarcoma to different chemotherapy agents using tissue cultures in the laboratory. We know that different chemotherapy agen...

Detailed Description

Investigators successfully established a miniaturized system that allows the setup of hundreds of wells and perform assays with minimal manipulation. The adapted geometry used to plate tumor cells in ...

Eligibility Criteria

Inclusion

  • Inclusion / exclusion criteria - Group1:
  • \- Patients without diagnosis of osteosarcoma and whose imaging studies are suggestive of osteosarcoma and who are planned to undergo biopsy or surgery for diagnostic purposes
  • Inclusion / exclusion criteria - Group 2:
  • \- Patients whose imaging studies are suggestive of metastatic osteosarcoma and who are planned to undergo biopsy or surgery for diagnostic purposes

Exclusion

    Key Trial Info

    Start Date :

    February 12 2024

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    January 1 2027

    Estimated Enrollment :

    40 Patients enrolled

    Trial Details

    Trial ID

    NCT06064682

    Start Date

    February 12 2024

    End Date

    January 1 2027

    Last Update

    July 15 2025

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    UCLA / Jonsson Comprehensive Cancer Center

    Los Angeles, California, United States, 90095