Status:
RECRUITING
The Role of Inflammation in Myocardial Infarction
Lead Sponsor:
Nicosia General Hospital
Collaborating Sponsors:
Aristotle University Of Thessaloniki
Hippocration General Hospital
Conditions:
Myocardial Infarction
Eligibility:
All Genders
18+ years
Brief Summary
The aim of this research is to study the prognostic role of a selected combination of cytokines and adipokines in patients with myocardial infarction, as well as to determine their role in the develop...
Detailed Description
After an acute myocardial infarction (AMI) the inflammatory response seems to have a central role and is connected to major adverse outcomes such as ischemia-reperfusion injury, adverse cardiac remode...
Eligibility Criteria
Inclusion
- ACS (ST-ACS, NSTE-ACS, UA) referred for coronary angiography
- Above 18 years old
- Consent form obtained
Exclusion
- Chronic Renal Failure (CRF) stage IV (e GFR \< 29 ml/min or creatinine \> 2 mg/dl)
- Chronic Liver Disease (CLD) (ALT \> 2 times upper normal limit)
- Chronic Inflammation and/or autoimmune diseases
- Active Ca
- Recent CVA (less than 1 month)
- Recent (within 2 weeks) use of glucocorticoid drugs or immunosuppressive agents
- Acute or chronic infection, major surgery, or trauma in the last month
- Previous heart transplantation
- Poor life expectancy
- Cardiogenic shock
- Cardiac arrest
Key Trial Info
Start Date :
August 24 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 30 2025
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT06065514
Start Date
August 24 2023
End Date
May 30 2025
Last Update
November 22 2024
Active Locations (4)
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1
Nicosia General Hospital
Nicosia, Cyprus, 2029
2
1st University Department of Cardiology - AHEPA University Hospital
Thessaloniki, Greece
3
2nd University Department of Cardiology
Thessaloniki, Greece
4
3rd University Department of Cardiology
Thessaloniki, Greece