Status:

UNKNOWN

Exploring Cancer-Associated Thromboembolism Prognosis Biomarkers and Polymorphisms

Lead Sponsor:

Lebanese University

Collaborating Sponsors:

Haykel Hospital

Conditions:

Cancer

Solid Tumor

Eligibility:

All Genders

18+ years

Phase:

PHASE1

Brief Summary

This study aims to assess biomarkers and their related polymorphisms in the context of cancer-associated thromboembolism, with a particular focus on their interaction with the immune system. The roles...

Detailed Description

Cancer, especially solid tumors, remains a significant global health challenge despite ongoing advancements in risk factor identification and targeted therapies. Among the various complexities of canc...

Eligibility Criteria

Inclusion

  • Individuals of white ethnicity.
  • Age between \> 18
  • Both males and females.
  • Diagnosis of selected cancer type (e.g., colorectal cancer).
  • Cancer stage 0/I/II without metastasis or lymph node dissemination at the time of enrollment.
  • No previous cancer therapy (radiotherapy, chemotherapy, or immunotherapy) received before study enrollment.
  • Unrelated patients.

Exclusion

  • Cancer stage III/IV.
  • History of hematological cancer types or previous cancers, recurrent or relapse.
  • Diagnosis of inflammatory bowel diseases.
  • Pre-existing cardiovascular diseases or coronary artery diseases.
  • Confirmed treated or untreated autoimmune diseases.
  • Metabolic disorders, diabetes, or hypertension.
  • Neurological diseases.
  • Evidence of cardiac, renal, bone, or cerebral damage.
  • Presence of more than one type of malignancies.
  • Active infections or myositis.
  • Familial polyposis.
  • Alcohol or smoking habits.
  • Colon-affecting food allergies.
  • Body mass index (BMI) \>30.
  • Significant weight loss within the last 2 years.
  • History of abdominal surgeries.
  • Pregnancy.
  • Related patients.

Key Trial Info

Start Date :

February 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2024

Estimated Enrollment :

500 Patients enrolled

Trial Details

Trial ID

NCT06065592

Start Date

February 1 2019

End Date

December 1 2024

Last Update

October 6 2023

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Haykel Hospital

Tripoli, North Lebanon, Lebanon, 961

2

Lebanese University

Tripoli, North Lebanon, Lebanon, 961