Status:
NOT_YET_RECRUITING
Tissue and Serum Level of NLRP1, NLRP3 and Il-18 in Early Stages of mf Patients
Lead Sponsor:
Cairo University
Conditions:
Early Disease Onset
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
To compare tissue and serum level of NLRP1, NLRP3 inflammasomes and Interleukin (IL)-18 in mycosis fungoids patients and normal controls. To compare tissue and serum level of NLRP1, NLRP3 inflammasom...
Detailed Description
Thirty patients with early stage mycosis fungoids and thirty normal healthy controls will be recruited. An informed written consent will be obtained from all patients and controls. Data collection De...
Eligibility Criteria
Inclusion
- New patients with early stages of mycosis fungoids (patch and plaque stage).
- Both genders
- Age group ≥ 18 years old.
Exclusion
- Patients with late stages mycosis fungoids (Tumor stage).
- Patients with absolute contraindication to phototherapy (e.g. any other skin cancers or photosensitivity); or to psoralen (e.g. liver disease).
- Subjects with history of solid or hematological malignancy as leukemia.
- Patients with autoimmune disease (e.g. SLE).
- Patients who received treatment of mycosis fungoids for the past one month.
- Pregnant and lactating females.
Key Trial Info
Start Date :
February 15 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 30 2024
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06066554
Start Date
February 15 2024
End Date
May 30 2024
Last Update
February 6 2024
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