Status:
UNKNOWN
Analysis of Calcium Score of Severe Aortic Stenosis in Patients With and Without Cardiac Amyloidosis (CAUSATIVE Study)
Lead Sponsor:
University Hospital of Ferrara
Conditions:
Amyloidosis Cardiac
Aortic Stenosis, Severe
Eligibility:
All Genders
65+ years
Brief Summary
The concomitant presence of cardiac amyloidosis (CA) in patients with aortic stenosis (AS) may challenge the estimation of stenosis degree. In patients with dual pathology (AS + CA) the most frequent ...
Detailed Description
Aortic stenosis (AS) is the most common valvular pathology in the elderly population, and there is an anticipated increase in prevalence and associated costs for treating this condition in the future....
Eligibility Criteria
Inclusion
- signed informed consent
- age ≥65 years old
- severe AS
- planned or performed TAVI/SAVR
- at least one red-flag suggestive of CA
- availability of EKG-gated CT
- availability of echocardiogram performed before TAVI/SAVR
- availability of bone scintigraphy performed within 1 year from CT
Exclusion
- • suboptimal acoustic window that may undermine the assessment of AS severity and phenotype profiling
Key Trial Info
Start Date :
June 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 1 2024
Estimated Enrollment :
480 Patients enrolled
Trial Details
Trial ID
NCT06066632
Start Date
June 1 2023
End Date
June 1 2024
Last Update
October 4 2023
Active Locations (1)
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1
University Hospital of Ferrara
Ferrara, Italy, 44124