Status:

RECRUITING

U-LABA/ICS Effects on Exercise Performance, Indacaterol

Lead Sponsor:

Morten Hostrup, PhD

Conditions:

Exercise Performance

Eligibility:

All Genders

18-39 years

Phase:

NA

Brief Summary

The purpose of the project is to investigate exercise performance in humans following bronchodilation induced by acute inhalation of beta2-agonist indacaterol + mometasonefuroate

Eligibility Criteria

Inclusion

  • Age 18-39
  • Physically active \> 5 h weekly
  • Maximal oxygen consumption classified as high or very high

Exclusion

  • Diagnosed with severe asthma and been in treatment with long-acting beta2-agonist/corticosteroid
  • ECG abnormality
  • ACQ score \> 1.5
  • Severe bronchial hyperreactivity as determined by mannitol test
  • FEV1/FVC ratio \< 0.7 determined with spirometry
  • Chronic illness determined to be a potential risk for participant during study
  • In chronic treatment with medication that may interfere with study results
  • Pregnancy
  • Smoker
  • Blood donation during the past 3 months

Key Trial Info

Start Date :

January 15 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2026

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT06067100

Start Date

January 15 2024

End Date

December 1 2026

Last Update

April 9 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

August Krogh Building

Copenhagen, Denmark, 2100