Status:

RECRUITING

Estimation of the Dietary Requirement for Vitamin D in Ethnic Groups

Lead Sponsor:

University of Surrey

Collaborating Sponsors:

University of Reading

Conditions:

Vitamin D Deficiency

Immune Health

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The aim of this study is to perform a double-blind, randomised, dose-response trial of vitamin D3 supplementation in United Kingdom (UK)-dwelling adults of white European, South Asian, and black Afric...

Detailed Description

The aim of this study is to perform a double-blind, randomised, dose-response trial of vitamin D3 supplementation in United Kingdom (UK)-dwelling adults of white European, South Asian, and black Afric...

Eligibility Criteria

Inclusion

  • British white European, black African/Caribbean, or South Asian (self-reported)
  • Living in England for \>2 months
  • Aged \>18 years
  • No significant health issues
  • English or Urdu speaker

Exclusion

  • Medical condition or history which might impact study measurements (e.g., ischaemic heart disease, type 1 and type 2 diabetes, thyroid disease, osteoporosis, haematological disease, malignancy)
  • Medications known to affect vitamin D metabolism (i.e., hormone replacement therapy, anti-oestrogens treatment, antiepileptic drugs, and breast cancer treatment)
  • Pregnant or planning pregnancy during the study period
  • Regular use of sun beds
  • Having a sun holiday one month prior to commencing study or plans for a sun holiday within the study period. A sun holiday is generally defined as a holiday in a sunny resort outside of the UK. The researchers will assess this on a case-by-case basis depending on the time of year and expected weather conditions
  • Reported participation in another clinical trial occurring simultaneously
  • Previous intolerance or allergic reaction to vitamin D

Key Trial Info

Start Date :

November 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2025

Estimated Enrollment :

114 Patients enrolled

Trial Details

Trial ID

NCT06067477

Start Date

November 1 2023

End Date

September 1 2025

Last Update

May 10 2024

Active Locations (1)

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1

Faculty of Health and Medical Sciences

Guildford, United Kingdom, GU2 7XH