Status:
COMPLETED
Effects of Fluid Resuscitation on Capillary Refilling Time and Organ Functions in Septic Shock
Lead Sponsor:
Samsun University
Conditions:
Sepsis
Eligibility:
All Genders
18-90 years
Brief Summary
Since the ultimate target of resuscitation is the microcirculation, normal microcirculatory perfusion appears to be the primary target of ideal resuscitation in septic shock patients. In septic shock ...
Detailed Description
An aggressive approach to fluid resuscitation in patients with sepsis is recommended by international guidelines and is considered the cornerstone of treatment. This approach is based on historical co...
Eligibility Criteria
Inclusion
- Inclusion Criteria
- Over 18 years old
- Admitted to intensive care with a diagnosis of sepsis or septic shock
- Systolic blood pressure \< 90 mmHg or Mean blood pressure \< 65 mmHg
- Those who need vasopressor medication
- Urine output \< 0.5 ml/kg/h for at least two hours
- Tachycardia (Heart rate \> 100/min)
- Serum Lactate \> 2 mmol/L
- Patients with central venous oxygen saturation (ScvO) \< 70%
- Exclusion Criteria
- Not approved by the patient or his/her guardian
- Known heart, kidney, liver failure
- The initial cause of shock is neurogenic, cardiogenic or obstructive shock.
- Pregnancy or suspected pregnancy
- Those with amputation or severe organ ischemia
- Those with peripheral artery disease
- Cannot be evaluated optimally with transthoracic echo
- Patients who died in the first 24 hours
Exclusion
Key Trial Info
Start Date :
October 25 2023
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 5 2026
Estimated Enrollment :
44 Patients enrolled
Trial Details
Trial ID
NCT06067516
Start Date
October 25 2023
End Date
January 5 2026
Last Update
January 7 2026
Active Locations (1)
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1
Samsun University
Samsun, Ilkadim, Turkey (Türkiye), 55090