Status:
ENROLLING_BY_INVITATION
Low Dose Dexmedetomidine as a Postoperative Pain Adjunct
Lead Sponsor:
Nichole Doyle
Conditions:
Spinal Fusion
Adolescent Idiopathic Scoliosis
Eligibility:
All Genders
10-21 years
Phase:
PHASE4
Brief Summary
This randomized controlled trial examines whether the addition of a low-dose dexmedetomidine infusion to our current multimodal pain management plan decreases narcotic consumption and reduces side eff...
Detailed Description
Patients will assigned to one of two groups. Either the intervention group where they will receive a dexmedetomidine infusion at 0.2mcg/kg/hr for 24 hours post-operatively or the control group where t...
Eligibility Criteria
Inclusion
- Diagnosis of idiopathic scoliosis
- Undergoing a posterior spinal fusion of at least 5 levels with both thoracic and lumbar involvement
Exclusion
- Known allergy to dexmedetomidine or any of the standard medications used intra or post operatively
- Patients with a history of chronic pain currently taking opioids, TCA's, Gabapentinoids
- Medical contraindications to administration of dexmedetomidine, unstable cardiac status, (prolonged Qtc, life threatening arrhythmias, use of digoxin)
- Moya Moya disease
Key Trial Info
Start Date :
July 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2026
Estimated Enrollment :
160 Patients enrolled
Trial Details
Trial ID
NCT06067893
Start Date
July 1 2024
End Date
July 1 2026
Last Update
December 22 2025
Active Locations (1)
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1
Children's Mercy Hospital
Kansas City, Missouri, United States, 64108