Status:

UNKNOWN

COMPARATIVE ANALYSIS OF THE MORPHO-MECHANICAL PROPERTIES OF RED BLOOD CELLS EXTRACTED FROM DIABETIC PATIENTS WITH AND WITHOUT MICROVASCULAR COMPLICATIONS

Lead Sponsor:

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Conditions:

Diabetes Mellitus, Type 1

Eligibility:

All Genders

50-70 years

Brief Summary

The aim of the study is to analyse the biomechanical stiffness of red blood cells extracted from subjects with type I diabetes with and without microvascular complications through a biophysical charac...

Eligibility Criteria

Inclusion

  • Diagnosis of type 1 diabetes for at least 10 years
  • Stable metabolic control (HbA1c \<7.5%) for at least 6 months
  • BMI between 18.5 and 30 Kg/m\^2
  • Systolic blood pressure \< 140 mmHg and diastolic blood pressure \<90 mmHg

Exclusion

  • Blood pressure higher than 140/90 mmHg
  • Unstable metabolic control (HbA1c \>7.5%)
  • BMI \> 30 Kg/m\^2 or \< 18.5 Kg/m\^2
  • Liver failure
  • Concomitant acute infections
  • Uncontrolled thyroid diseases
  • Pregnancy

Key Trial Info

Start Date :

September 29 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 29 2025

Estimated Enrollment :

48 Patients enrolled

Trial Details

Trial ID

NCT06068205

Start Date

September 29 2023

End Date

September 29 2025

Last Update

October 5 2023

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