Status:
RECRUITING
A Prospective Study on the Prediction Model of Para-aortic Lymph Node Metastasis
Lead Sponsor:
Chongqing University Cancer Hospital
Conditions:
Locally Advanced Cervical Cancer
Eligibility:
FEMALE
18-75 years
Phase:
NA
Brief Summary
The goal of this prospective single-arm trial is to investigate the accuracy and feasibility of the para-aortic lymph node metastasis prediction model in locally advanced cervical cancer, as well as i...
Eligibility Criteria
Inclusion
- In 2018, the International Federation of Obstetrics and Gynecology (FIGO) stage was Ib3 IIA2-IVA;
- It was treated initially without surgical and chemotherapy.
- Squamous cell carcinoma, adenocarcinoma and adeno-squamous cell carcinoma were confirmed by histopathology.
- Pelvic MRI ± abdominal CT or MRI or PET/CT were performed before treatment.
- ECOG score:0 \~ 1.
- The expected survival time\>6 months;
- There is no absolute contraindication of surgery and and chemoradiotherapy and the patients with good compliance.
Exclusion
- History of immune disease who need to take immunosuppressive drugs.
- History of serious mental illness and brain functional disorder.
- Other malignancies were diagnosed within five years or needed treatments.
- Those who are unable or unwilling to accept surgical treatment/sign informed consent/comply with research requirements.
- Without surgical conditions: 1) Chronic renal insufficiency or renal failure; 2) Liver insufficiency; 3)Chronic lung disease with restrictive respiratory dysfunction; 4) Cardiac dysfunction (patients with relative and absolute contraindications to surgery after consultation by cardiac physicians.
- Patients who cannot understand the research regimen and refuse to sign the informed consent form.
- Other concomitant diseases or special conditions seriously endanger the patient's health or interfere with the trial.
Key Trial Info
Start Date :
March 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 28 2026
Estimated Enrollment :
264 Patients enrolled
Trial Details
Trial ID
NCT06068387
Start Date
March 1 2023
End Date
February 28 2026
Last Update
October 10 2023
Active Locations (1)
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1
Chongqing University Cancer Hospital
Chongqing, China