Status:

COMPLETED

The Potential Impact of Clindamycin on Neurosurgery Patients.

Lead Sponsor:

Damanhour University

Conditions:

Neurologic Complication

Neurosurgery

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

A prospective, open-label, single center, controlled trial. 44 patients that underwent neurosurgery or presented meningitis signs, for whom Clindamycin add-on therapy to assess its effect on neurologi...

Detailed Description

1. This is a prospective, open-label, single center, controlled trial. 44 patients that underwent neurosurgery or presented meningitis signs, for whom Clindamycin add-on therapy is prescribed (900 - 1...

Eligibility Criteria

Inclusion

  • Inclusion criteria
  • 1\) Adult patients will be enrolled if they underwent neurosurgery or presented with clinical signs of meningitis.
  • Exclusion criteria
  • Age lower than 18.
  • Females with a positive pregnancy test.
  • Known congestive heart failure or ischemic heart disease.
  • Any injury that disturbs the examination (high cervical cord injury or locked-in syndrome, could be a source of bias).
  • Severe brain disease (For example CVA history or brain tumor).
  • Renal failure with GFR lower than 60 ml/min.
  • Patients with unknown identity.

Exclusion

    Key Trial Info

    Start Date :

    March 1 2023

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    December 30 2023

    Estimated Enrollment :

    44 Patients enrolled

    Trial Details

    Trial ID

    NCT06068673

    Start Date

    March 1 2023

    End Date

    December 30 2023

    Last Update

    January 19 2024

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    Alexandria University Hospital

    Alexandria, Egypt