Status:

RECRUITING

Detection of Azole Resistance Inducing Mutations on DNA Extracted Directly From Serum or Plasma of Immunocompromised Patients With an Invasive Aspergillus Infection Azole Resistance PCR Optimalization-study

Lead Sponsor:

Bart Rijnders

Conditions:

Invasive Aspergillosis

Eligibility:

All Genders

18+ years

Brief Summary

Invasive aspergillosis (IA) is the most common mould infection in immunocompromised patients with haematological disease. Voriconazole, a triazole, improves overall survival of patients with an IA and...

Eligibility Criteria

Inclusion

  • 18 years or older.
  • Lung CT shows lesions that fulfil the EORTC/MSG radiological criteria of possible invasive fungal infection.
  • A bronchoalveolar lavage is planned or has been performed \<48hrs earlier

Exclusion

  • \- Patients unable or unwilling to provide consent

Key Trial Info

Start Date :

July 1 2017

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2030

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT06069505

Start Date

July 1 2017

End Date

December 31 2030

Last Update

May 7 2024

Active Locations (1)

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1

Erasmus Medical Center (EMC)

Rotterdam, South Holland, Netherlands, 3000 CA