Status:
RECRUITING
The Effects of Almond on Facial Skin Collagen and Wrinkles
Lead Sponsor:
Integrative Skin Science and Research
Conditions:
Collagen Degeneration
Wrinkle
Eligibility:
FEMALE
35-70 years
Phase:
NA
Brief Summary
Investigate the effects of almond consumption on collagen production, elastin levels, wrinkles, and pigmentation among premenopausal women and postmenopausal women belonging to all Fitzpatrick skin ty...
Detailed Description
Almonds are energy-dense and rich in beneficial nutrients including B vitamins, vitamin E, mono- and polyunsaturated fatty acids, protein, fiber, minerals and polyphenols. Polyphenols and vitamin E in...
Eligibility Criteria
Inclusion
- Subjects 35 to 70 years of age of all skin types
- 50% of the subjects will be postmenopausal women determined as \>1-year loss of menstrual period
- 50% of the subjects will be premenopausal women
- BMI 18.5 - 35 kg/m2
- Individuals with a habitual diet that has been maintained for at least 6 months and to be maintained for the duration of the study
- Individuals must maintain their usual skincare products, defined as products that has been used for at least 1 month, for the duration of the study
Exclusion
- Those with a nut allergy
- Those who are unwilling to discontinue oral collagen supplementation 1 month prior to the start of the study
- Individuals who are unwilling to discontinue vitamin E or nut containing supplements 2 weeks prior to and during the intervention.
- Individuals who are pregnant or breastfeeding
- Change in skincare products during the study
- Had a medical or cosmetic procedure such as laser resurfacing or plastic surgery to the face within the last 6 months (include botulinum toxin, dermal fillers, collagen, or other similar cosmetic procedure)
- Has an autoimmune photosensitive condition or known genetic condition with a deficiency in collagen production (such as Ehler-Danlos)
- Those with a skin disease on their face that would affect the assessment of their skin based on the assessment of the investigator.
- Current tobacco smoker or a tobacco smoking history of greater than 10 pack-years
Key Trial Info
Start Date :
October 4 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2024
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06074276
Start Date
October 4 2023
End Date
December 31 2024
Last Update
June 18 2024
Active Locations (1)
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1
Integrative Skin Science and Research
Sacramento, California, United States, 95819