Status:
RECRUITING
Sex Difference of Coronary Microvascular Dysfunction in Patients With Non-obstructive Coronary Artery Disease
Lead Sponsor:
Korea University Anam Hospital
Conditions:
Microvascular Angina
Eligibility:
All Genders
20-80 years
Brief Summary
Sex difference of coronary microvascular dysfunction evaluated by coronary flow reserve will be assessed in patients with non-obstructive coronary artery disease
Detailed Description
The investigators will select consecutive patients who experienced chest pain but had no significant coronary artery stenosis (\<50% stenosis). Coronary microvascular function will be evaluated by ade...
Eligibility Criteria
Inclusion
- Typical/atypical chest pain or ischemic symptoms including dyspnea
- No significant coronary artery stenosis (\<50% stenosis) in coronary angiography or computed tomography
Exclusion
- ≥ Moderate valvular heart disease
- Congenital heart disease
- Chronic renal failure (estimated glomerular filtration rate \<30 ml/min/1.73m2) or end-stage renal failure undergoing hemodialysis or peritoneal dialysis
- Asthma, chronic obstructive pulmonary disease and primary pulmonary hypertension
- Receiving anticancer drugs
- Vasculitis associated with autoimmune diseases
- Atrioventricular block with more than second degrees, symptomatic bradycardia, cryo-node failure syndrome, Wolff-Parkinson-White (WPW) patients
Key Trial Info
Start Date :
February 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT06076551
Start Date
February 1 2018
End Date
December 31 2025
Last Update
March 26 2025
Active Locations (1)
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1
Korea University Anam Hospital
Seoul, South Korea, 02841