Status:

COMPLETED

Impact of Multiple Electrolytes Injection Ⅱ and Saline on Hyperchloremia in Patients With Aneurysmal Subarachnoid Hemorrhage:a Pilot Study

Lead Sponsor:

Capital Medical University

Conditions:

Aneurysmal Subarachnoid Hemorrhage

Hyperchloremia

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

The goal of this pilot randomized trial is to compare the effect of Multiple Electrolytes Injection Ⅱand saline on the occurrence of hyperchloremia within 72h of randomization in patients with aneurys...

Detailed Description

Background: The isotonic solutions commonly used in ICUs are saline (0.9% sodium chloride) and balanced crystalloid solutions (Ringer's solution, multiple electrolytes injection, etc.). Studies have ...

Eligibility Criteria

Inclusion

  • Patients with aneurysmal subarachnoid hemorrhage;
  • Expected ICU stay \> 24 hours.

Exclusion

  • Under 18 years of age;
  • Pregnancy;
  • Patients at imminent risk for death within 24 hours;
  • Patients with a known history of serious cardiovascular, respiratory, kidney, liver, blood, or immune disease;
  • Azotemia (BUN \> 200μmol/L), hypokalemia (blood potassium \< 2.5mmol/L), hypocalcemia (blood calcium \< 1.8mmol/L);
  • Patients routinely receiving renal replacement therapy (RRT);
  • Declined to participate in the study.

Key Trial Info

Start Date :

November 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 31 2023

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT06076590

Start Date

November 1 2021

End Date

May 31 2023

Last Update

October 11 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

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ICU, Beijing Tiantan Hospital, Capital Medical University

Beijing, Beijing Municipality, China, 100070