Status:
RECRUITING
Danish Angle Closure Prevention Trial
Lead Sponsor:
University of Aarhus
Conditions:
Primary Angle Glaucoma Closure Suspect
Eligibility:
All Genders
40-80 years
Phase:
NA
Brief Summary
To determine whether primary angle closure suspects (PACS) in a Caucasian population benefit from prophylactic laser iridotomy.
Detailed Description
Prospective, randomised paired-eye design clinical trial comparing peripheral laser iridotomy in one eye with observation in the other over 5-years follow-up.
Eligibility Criteria
Inclusion
- Primary angle closure suspect: ≥180 degrees (cumulative) irido-trabecular contact on darkroom gonioscopy, IOP\<21mmHg, no peripheral anterior synechiae, no glaucomatous optic neuropathy
- Best-corrected visual acuity (BCVA) \>0.8 on both eyes
- Caucasian
Exclusion
- Pseudophakia
- Previous iridotomy
- Clinically significant cataract with indication for surgery,
- Gaucoma
- Uveitis
- Unstable retinal conditions
- Ocular malignancies
- PEX
- PDS
- Systemic or ocular corticosteroid treatment
Key Trial Info
Start Date :
September 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2029
Estimated Enrollment :
242 Patients enrolled
Trial Details
Trial ID
NCT06077253
Start Date
September 1 2023
End Date
September 1 2029
Last Update
November 13 2023
Active Locations (5)
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1
Aalborg University Hospital
Aalborg, Denmark, 9000
2
Aarhus University Hospital
Aarhus, Denmark, 8240
3
Rigshospitalet Glostrup
Glostrup Municipality, Denmark, 2600
4
Odense University Hospital
Odense, Denmark, 5000