Status:

COMPLETED

Comparison of Efficacy and Ocular Surface Assessment Between BRIDIN-plus and Combigan in Glaucoma or Ocular Hypertensive

Lead Sponsor:

CHA University

Collaborating Sponsors:

Hanlim Pharm. Co., Ltd.

Conditions:

Glaucoma

Ocular Hypertensive

Eligibility:

All Genders

19+ years

Phase:

PHASE4

Brief Summary

Comparison of Efficacy and Ocular Surface Disease Assessment between BRIDIN-plus Eye drops and Combigan Eye drops in Glaucoma or Ocular Hypertensive Patients : Phase 4, Parallel Group Design, Investig...

Detailed Description

The purpose of this clinical trial is to prove lower negative effects on ocular surface disease and higher patient compliance of a single-use formula BRIDIN-PLUS® eye drops group, comparing to a multi...

Eligibility Criteria

Inclusion

  • Inclusion Criteria
  • Male or female adults who are 19 years or older with a diagnosis of glaucoma or intraocular hypertension
  • A person who has completed an appropriate washout period if glaucoma treatment medication has been used
  • Intraocular pressure measured by Goldman applanation tonometer at visit 2 is 15mmHg or above and less than 40mmHg
  • A person who has signed the written consent form by himself/herself or by a legal representative
  • Exclusion Criteria:
  • A patient with primary close angle glaucoma, congenital glaucoma, secondary glaucoma caused by steroids
  • Best corrected visual acuity of both eyes measured by Snellen acuity charts is 20/80 (decimal 0.25) or less
  • A patient with progressive intraocular inflammation
  • Central corneal thickness is less than 470um or greater than 591ums
  • A patient who has had lacrimal punctual occlusion done within the last 3 monthds or who has eye surgery plan during the clinical study
  • Pregnant or lactating women
  • Other cases if investigators judge the patient is difficult to participate the clinical trial

Exclusion

    Key Trial Info

    Start Date :

    October 8 2021

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    December 23 2022

    Estimated Enrollment :

    60 Patients enrolled

    Trial Details

    Trial ID

    NCT06078592

    Start Date

    October 8 2021

    End Date

    December 23 2022

    Last Update

    March 26 2025

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    Seungsoo Rho

    Seoul, Seongnam, Bundang-gu, South Korea, 13497