Status:
RECRUITING
Effect of Anti-inflammatory Diet in Osteoarthritis
Lead Sponsor:
University of California, San Diego
Conditions:
Osteoarthritis, Knee
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
In a previous exploratory study, the investigators observed an effect on disease activity outcomes of anti-inflammatory diet. The investigators also observed change in microbiome and circulating metab...
Eligibility Criteria
Inclusion
- Unilateral radiographic symptomatic KOA
- No changes in therapy during the previous 3 months
- Interested in dietary intervention and able to provide consent and attend follow-up visits
Exclusion
- Previous knee surgery
- Severe radiographic disease (KL grade 4)
- Rheumatoid Arthritis
- Any Abnormal blood values in the comprehensive metabolic panel test at screen (Abnormality will be defined based on standard reference ranges)
- Use of corticosteroids and/or intra-articular injections during the preceding 3 months
- Use of fish oils and glucosamine
- Participation in a weight loss program in the preceding 6 months
- Recent changes in physical activity levels
- Regular smoking
- Patients with food allergies
- Patient with other medical conditions that will impair the ability to participate in a nutritional study
- Plan to change systemic therapy
- Patients unwilling to change dietary habits
Key Trial Info
Start Date :
October 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2026
Estimated Enrollment :
72 Patients enrolled
Trial Details
Trial ID
NCT06080347
Start Date
October 1 2023
End Date
January 1 2026
Last Update
November 4 2024
Active Locations (1)
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1
University of California
San Diego, California, United States, 92122