Status:
RECRUITING
The Choice of Treatment Methods and Efficacy of LABC
Lead Sponsor:
Peking Union Medical College Hospital
Conditions:
Locally Advanced Breast Cancer
Eligibility:
FEMALE
18-70 years
Phase:
NA
Brief Summary
The goal of this clinical trial is to compare the therapeutic effects of chemotherapy followed by surgery and surgery followed by chemotherapy in patients with locally advanced breast cancer（LABC). Pa...
Detailed Description
Local advanced breast cancer was enrolled in the Department of Breast Surgery of Peking Union Medical College Hospital and Beijing Cooperation Hospital according to the criteria for patient inclusion....
Eligibility Criteria
Inclusion
- 18-70 year old female
- Patients with locally advanced breast cancer (stage IIIb - IIIc) first diagnosed;
- Clinical diagnosis of breast cancer, or puncture pathology suggests breast cancer;
- After evaluation by experienced clinical physicians, the patient's tumor has the possibility of surgical resection. Specific evaluation indicators include ultrasound assessment of the tumor not surrounding the axillary vein;
- Accept treatment plans including surgery, radiotherapy, and chemotherapy;
- Volunteer to participate in clinical research and sign an informed consent form;
- Willing to undergo follow-up and complete quality of life (EQ-5D series scale and FACT-B scale) and postoperative psychological status (Anxiety/Depression Self Rating Scale) assessments;
Exclusion
- Patients under 18 years old or over 70 years old;
- Those who have received breast cancer related surgery, radiotherapy or chemotherapy;
- Those who are not expected to receive surgery, radiotherapy or chemotherapy related to breast cancer
- History of other malignant tumors;
- Pregnant or lactating women;
- Accompanying active infection and fever;
- Other serious diseases that may significantly affect clinical trial compliance, such as severe cardiopulmonary dysfunction, liver and kidney dysfunction, poorly controlled diabetes and mental illness.
Key Trial Info
Start Date :
October 8 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2026
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT06080620
Start Date
October 8 2023
End Date
August 1 2026
Last Update
October 12 2023
Active Locations (1)
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1
Ying Xu
Beijing, China, 100730