Status:
COMPLETED
Can Instrumentation Kinematics Affect Post Operative Pain and Substance P Levels? A Randomized Controlled Trial
Lead Sponsor:
Ain Shams University
Conditions:
Pain, Postoperative
Irreversible Pulpitis
Eligibility:
All Genders
20-50 years
Phase:
NA
Brief Summary
The aim of this study was to evaluate the effect of continuous rotation and reciprocation kinematics on post operative pain and difference in substance P levels in patients with irreversible pulpitis ...
Eligibility Criteria
Inclusion
- Single rooted mandibular second premolar teeth with complete root formation
- Pulpal diagnosis: Symptomatic irreversible pulpitis
- Periapical diagnosis: symptomatic apical periodontitis with no visible periapical radiolucent area
- Patients with pre-operative pain records above 4 on Numerical Rating Scale (NRS) to ensure standardization
Exclusion
- The presence of any systemic disease or allergic reactions
- Pregnant and lactating females
- Patients on antibiotic or anti-inflammatory medication
- Use of analgesics a week prior to treatment
- A radiographically untraceable canal or an excessively curved root
- The presence of periapical radiolucency or sinus tract.
- Teeth with open apices
- Severe periodontal disease (generalized or localized to the tooth in question)
- Absence of bleeding in the pulp chamber on access cavity preparation
- Internal or external resorption
Key Trial Info
Start Date :
March 15 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 5 2023
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06081335
Start Date
March 15 2023
End Date
June 5 2023
Last Update
November 15 2023
Active Locations (2)
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1
Ain Shams University
Cairo, Select A State Or Province, Egypt, 11765
2
Ain Shams University
Cairo, Egypt, 11765