Status:

RECRUITING

Validating Immunological Markers Associated With Mental Fatigue in Graves' Disease

Lead Sponsor:

Vastra Gotaland Region

Conditions:

Graves Disease

Mental Fatigue

Eligibility:

All Genders

18-72 years

Brief Summary

Mental fatigue occurs in many diseases and the reasons are mostly unknown. The investigators hypothesize that remaining mental fatigue after restored euthyroidism in Graves' disease is an autoimmune c...

Eligibility Criteria

Inclusion

  • Recently diagnosed Graves' disease
  • Positive thyroid stimulating hormone (TSH)-receptor antibodies (TRAb)
  • Thyroid hormones above the upper reference limit
  • Inclusion within three weeks after start of antithyroid drugs
  • Controls: Matched for gender and age

Exclusion

  • Person unable to follow protocol as with psychosis, dementia or not able to answer questionnaires in Swedish.
  • Recidive of Graves' disease
  • Pregnancy
  • Controls: -Thyroid disease
  • Neurological disease

Key Trial Info

Start Date :

September 12 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 20 2025

Estimated Enrollment :

430 Patients enrolled

Trial Details

Trial ID

NCT06081439

Start Date

September 12 2019

End Date

December 20 2025

Last Update

November 18 2024

Active Locations (1)

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Endokrina Forskningsenheten, Sahlgrenska University Hospital

Gothenburg, Sweden, 41346