Status:

RECRUITING

FRAMED Infrainguinal Venous Bypass Versus Conventional Autologous Bypass Trial

Lead Sponsor:

Paracelsus Medical University

Conditions:

Peripheral Arterial Occlusive Disease

Femoropopliteal Artery Occlusion

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of this clinical trial is to analyze patency after autologous infrainguinal bypass surgery in patients receiving a venous conduit versus a covered venous conduit.

Detailed Description

Patients presenting to Vascular Surgical Units are usually multimorbid with increased cardiopulmonary risk. Autologous venous bypass is indicated in certain situations despite the longer duration of s...

Eligibility Criteria

Inclusion

  • Inclusion Criteria
  • Age at least 18 years
  • Informed consent form with signature
  • Rutherford Category 3 (\<200m) or chronic critical ischemia (Rutherford Category 4-6)
  • Assured inflow and recipient artery.
  • Exclusion Criteria
  • Pregnant or breastfeeding women
  • Active infection or sepsis
  • Acute ischemia
  • Endovascular procedure in the region to be treated.
  • Vein with outer diameter \<3.5 mm or \>8 mm under pressure.
  • Spliced Veins.
  • Known allergy to the cobalt-chromium alloy (ASTM 1058) or its components (Cobalt-Chromium-Iron-Nickel-Molybdenum).
  • Vasculitis
  • Coagulopathy
  • Radiation therapy near the anastomosis

Exclusion

    Key Trial Info

    Start Date :

    September 11 2023

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    September 1 2027

    Estimated Enrollment :

    110 Patients enrolled

    Trial Details

    Trial ID

    NCT06082466

    Start Date

    September 11 2023

    End Date

    September 1 2027

    Last Update

    November 21 2023

    Active Locations (1)

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    1

    University Hospital of Salzburg, Paracelsus Medical University

    Salzburg, Austria, 5020