Status:
RECRUITING
Evaluation of the Hemodynamic Effect of Dexmedetomidine in Scheduled Outpatient Surgery
Lead Sponsor:
Centre Hospitalier Universitaire de Nīmes
Conditions:
Anesthesia
Dexmedetomidine
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Ambulatory surgery is increasingly used in anesthesia. In case of general anesthesia, it is recommended to use anesthesia molecules with a short half-life and low doses of opiates to ensure a rapid aw...
Eligibility Criteria
Inclusion
- Patient with scheduled surgery under general anesthesia for one of the following: oral, orthopedic, urological, digestive and gynecological surgeries.
- The patient must have given their free and informed consent and signed the consent form
- The patient must be a member or beneficiary of a health insurance plan
Exclusion
- The subject is in a period of exclusion determined by a previous study
- The subject is unable to give consent
- It is impossible to give the subject informed information
- The patient is under safeguard of justice or state guardianship
- Patient with a known allergy to dexmedetomidine or other drugs.
- Patient with a contraindication to general anesthesia or outpatient management.
- Patient treated with beta-blocker, ACE inhibitor or ARB2
- Patient with an ASA4 score.
- Patient with HR \< 50 bpm.
- Patient with the following cardiovascular comorbidities: coronary insufficiency, obstructive cardiomyopathy, severe hypertension, ventricular rhythm or conduction disorder.
- Patient with hepatic (prothrombin rate \< 70%, liver enzyme/Bilirubin X 3) and/or renal (clearance \< 50 ml.min) insufficiency.
- Pregnant, parturient or nursing patient
Key Trial Info
Start Date :
October 19 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 1 2026
Estimated Enrollment :
594 Patients enrolled
Trial Details
Trial ID
NCT06082856
Start Date
October 19 2023
End Date
February 1 2026
Last Update
June 6 2025
Active Locations (1)
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1
CHU de Nîmes
Nîmes, France