Status:
ACTIVE_NOT_RECRUITING
Effects of Yeast Beta-glucan on Cognitive Function in Patients With Mild Cognitive Impairment
Lead Sponsor:
Xiaofan Xu
Conditions:
Mild Cognitive Impairment
Alzheimer Disease
Eligibility:
All Genders
50-80 years
Phase:
NA
Brief Summary
Patients with mild cognitive impairment aged 50-80 years old were recruited in Shiyan City, Hubei Province, and divided into intervention group and placebo group. They were given yeast β-glucan capsul...
Eligibility Criteria
Inclusion
- 1\. Aged 50-80 years;
- 2\. Permanent residents of Shiyan City;
- 3\. Meet the diagnostic criteria of MCI:
- 4\. Willing to cooperate in completing questionnaire survey and clinical examination, and sign informed consent;
- 5\. Did not participate in other clinical trials in the past 3 months.
Exclusion
- 1\. Alcohol or drug abuse;
- 2\. Patients with neurological diseases that may cause cognitive dysfunction, including cerebrovascular diseases, stroke, brain tumors, Parkinson's disease, active epilepsy, etc.;
- 3\. History of severe head trauma;
- 4\. Severe sensory and perceptual impairment, unable to complete the cognitive function measurement;
- 5\. History of mental illness such as depression, mania, anxiety, or take psychiatric drugs;
- 6\. Serious heart, lung, liver, kidney dysfunction, malignant tumors, etc.;
- 7\. Suffering from autoimmune diseases;
- 8\. Trauma, spinal injury or any disease that may affect the motor function of the limb;
- 9\. Recent infectious diseases, acute gastrointestinal diseases;
- 10\. Take antibiotics, probiotics, prebiotics or biostime products within the last 1 month.
Key Trial Info
Start Date :
June 27 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2025
Estimated Enrollment :
144 Patients enrolled
Trial Details
Trial ID
NCT06083350
Start Date
June 27 2023
End Date
June 30 2025
Last Update
May 14 2024
Active Locations (2)
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1
Sinopharm Dongfeng General Hospital
Shiyan, Hubei, China, 442000
2
Huazhong University of Science and Technology
Wuhan, Hubei, China, 430000