Status:

RECRUITING

Early Breast Growth in Girls Aged 6 to 8 Years in the Current Environmental Context

Lead Sponsor:

Lille Catholic University

Conditions:

Puberty, Precocious

Breast

Eligibility:

FEMALE

6-8 years

Phase:

NA

Brief Summary

Various studies show an increase in the number of cases of early puberty in girls with breast development with a variable clinical presentation and evolution. This increasing phenomenon concerns girls...

Eligibility Criteria

For patients:

Inclusion Criteria:

  • Girls aged 6 to 8 years
  • Presenting a breast development (isolated or not)
  • Undergoing scheduled pediatric day hospital care (HDJ)
  • Who agree to participate in the study
  • Whose parents agree to their child's participation in the study
  • French speaking
  • Whose parents speak French
  • Affiliated to social security

Exclusion Criteria:

  • Organic brain causes of precocious puberty: History of neurocerebral disease (malformations, developmental abnormalities)
  • Organic causes of precocious puberty: Mac Cune Albright syndrome, ovarian cyst or tumor and adrenal hyperplasia
  • History of chemotherapy or radiation therapy
  • Presenting with a communication disorder
  • Pregnancy
  • Persons under protective measures
  • Persons deprived of liberty for judicial or administrative reasons

For controls:

Inclusion Criteria:

  • Girls aged 6 to 8
  • Tanner stage 1: Absence of breasts and hairiness
  • Coming for routine consultation in the pediatric HDJ at Saint-Vincent-de-Paul hospital, or at the BLM practice in Lambersart, or to radiology for an MRI for another medical other medical reason
  • Agree to participate in the study
  • Whose parents agree to their child's participation in the the study
  • French-speaking
  • Whose parents speak French
  • Affiliated with social security

Exclusion Criteria:

  • Signs of puberty (Tanner stages 2, 3, 4 and 5 for breast development) breast development)
  • Previous chemotherapy or radiotherapy
  • Presenting a communication disorder
  • Pregnant women
  • Persons under protective supervision
  • Persons deprived of their liberty for judicial or administrative reasons

Key Trial Info

Start Date :

May 15 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 15 2027

Estimated Enrollment :

62 Patients enrolled

Trial Details

Trial ID

NCT06083415

Start Date

May 15 2023

End Date

May 15 2027

Last Update

March 17 2026

Active Locations (2)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 1 (2 locations)

1

Cabinet BLM

Lambersart, Hauts-de-France, France, 59130

2

Saint Vincent hospital

Lille, Hauts-de-France, France, 59000