Status:
ENROLLING_BY_INVITATION
CS1P1 PET Studies of Neuroinflammation in Parkinson Disease
Lead Sponsor:
Washington University School of Medicine
Conditions:
Parkinson Disease
Eligibility:
All Genders
50+ years
Brief Summary
Parkinson disease (PD) is a progressive neurological disorder strongly linked to advancing age that results in decline in mobility and thinking. Based on prior research, the investigators think that s...
Eligibility Criteria
Inclusion
- Parkinson Disease (PD) participants must be at least 50 years old and meet clinical diagnostic criteria of idiopathic PD.
- Control participants must be at least 50 years old and not have PD, no first-degree family member with PD, and no evidence of PD or dementia on examination.
Exclusion
- any history of other neurologic illness (e.g. stroke, seizure, multiple sclerosis)
- history of brain surgery or major head trauma
- major medical/systemic illness
- severe psychiatric illness (e.g. bipolar disorder, schizophrenia)
- major drug abuse
- history of long term use of anti-dopaminergic medication
- chronic treatment with immunomodulatory or anti-inflammatory medications
- weight over 300 lbs
- contraindication to or inability to tolerate MRI
Key Trial Info
Start Date :
January 10 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
February 28 2029
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT06084533
Start Date
January 10 2024
End Date
February 28 2029
Last Update
March 28 2025
Active Locations (1)
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1
Washington University School of Medicine
St Louis, Missouri, United States, 63105