Status:

UNKNOWN

The Efficacy of Amway Uric Acid Lowering Product on Hyperuricemia

Lead Sponsor:

Amway (China) R&D Center

Conditions:

Hyperuricemia

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

The goal of this three arms, randomized, double-blind controlled interventional study is to evaluate the efficacy of Amway uric acid lowering product improving hyperuricemia in patients aged 18 and 65...

Eligibility Criteria

Inclusion

  • Participants aged between 18 and 65 years old (mostly above 35 years old), including male and female and the ratio of male to female is not limited;
  • Patients with hyperuricemia: meet the diagnostic criteria set out in the "Chinese Guidelines for Diagnosis and Treatment of Hyperuricemia and Gout (2019)", and fasting blood uric acid level exceeds 420 μmol/L twice on different days. Further classification using the Janssens Gout Diagnostic scale included asymptomatic hyperuricemia (that is, never had a gout attack) and patients with a history of gout, with a ratio of about 1:1;
  • Participants agree not to take any drugs, supplements, or performance enhancers during the study, or they will be eliminated
  • Participants understand the test procedure, read, and sign an appropriate Informed Consent Form indicating their willingness to participate.

Exclusion

  • Secondary gout caused by kidney disease, blood disease, drug use, tumor radiotherapy and chemotherapy;
  • Subjects who are using drugs during gout attacks;
  • Malignant diseases: patients with severe lung, cardiovascular, blood and hematopoietic system, central nervous system or other system diseases, as well as tumor patients;
  • Severe obesity (BMI\>32kg/m2);
  • Abnormal liver and kidney function: abnormal level of alanine aminotransferase or aspartate aminotransferase; Serum creatinine was higher than the upper limit of the normal range;
  • Allergic to the test drug or weak or allergic;
  • Pregnant or lactating women or those who have pregnancy plans; Sex hormone replacement therapy and oral contraception in the past 3 months;
  • Subjects who have participated in other research projects within three months;
  • Subjects that other researchers considered should be excluded.

Key Trial Info

Start Date :

October 23 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 15 2024

Estimated Enrollment :

180 Patients enrolled

Trial Details

Trial ID

NCT06084585

Start Date

October 23 2023

End Date

March 15 2024

Last Update

October 16 2023

Active Locations (1)

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1

Charlie Zhang

Jinhua, Zhejiang, China