Status:

ENROLLING_BY_INVITATION

Effectiveness and Safety of Abluminal Biodegradable Polymer Sirolimus-eluting Stent (GENOSS® DES)

Lead Sponsor:

Genoss Co., Ltd.

Conditions:

Coronary Artery Disease

Percutaneous Coronary Intervention

Eligibility:

All Genders

19+ years

Brief Summary

In this study, the investigators evaluated the effectiveness and safety of using the GENOSS® DES, which has a biodegradable polymer only on the inner wall of the blood vessel, for patients(all-comers)...

Detailed Description

This study is a sponsor-initiated clinical trial (SIT) that enrolls patients who underwent percutaneous coronary intervention using the GENOSS® DES drug-eluting stent. As it is a prospective, multice...

Eligibility Criteria

Inclusion

  • \<Inclusion Criteria\>
  • Adults over 19 years of age
  • Patients with typical symptoms or objective evidence of myocardial ischemia and eligible for coronary angioplasty.
  • Severe coronary artery stenosis suitable for GENOSS® DES insertion
  • Patients who agree to the research protocol and clinical follow-up plan and give written informed consent in the consent form approved by the Institutional Review Board/Ethics Committee of each research institution.
  • \<Exclusion Criteria\>
  • Test subjects with known hypersensitivity or contraindications to the following drugs or substances: heparin, aspirin, clopidogrel, sirolimus, contrast medium (however, even subjects with hypersensitivity to contrast medium can be controlled by steroids and pheniramine) In this case, registration is possible, but if there is known anaphylaxis, it is excluded)
  • Patients who also received other drug-eluting stents
  • If you have a disease with a remaining life expectancy of less than 1 year
  • Pregnant or lactating women or women who may be pregnant
  • Cases in which the patient was admitted to the hospital due to psychogenic shock and the likelihood of survival is medically expected to be low.
  • Patients judged by researchers to be unsuitable for research

Exclusion

    Key Trial Info

    Start Date :

    July 15 2022

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    December 31 2027

    Estimated Enrollment :

    1000 Patients enrolled

    Trial Details

    Trial ID

    NCT06086496

    Start Date

    July 15 2022

    End Date

    December 31 2027

    Last Update

    October 6 2025

    Active Locations (1)

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    1

    Korea University Anam Hospital

    Seoul, Seoul, South Korea