Status:

UNKNOWN

Real-life Assessment of the Safety and Performance of the SYNOVIUM HCS Device

Lead Sponsor:

LCA Pharmaceutical

Collaborating Sponsors:

EVAMED

Conditions:

Gonarthrosis

Eligibility:

All Genders

18-90 years

Brief Summary

Patients who are to benefit from an injection of SYNOVIUM HCS as part of their care will be offered to participate in this study. Patients will need to sign a consent form to participate. Prior to SYN...

Detailed Description

Inclusion period: 6 months Follow-up period: * 6-month follow-up, after intra-articular injection with extension * 1 single syringe of SYNOVIUM HCS (3 mL), * Controls scheduled at 1 week, 1, 3,...

Eligibility Criteria

Inclusion

  • Adult patient
  • Patient with radiologically characterized gonarthrosis (stages Kellgren \& Lawrence grades I to III)
  • Patient with walking pain (WOMAC A1) at least equal to 2 on the Likert scale 0-4
  • Patient to benefit from an injection of SYNOVIUM HCS as part of his treatment
  • Patient agreeing to participate in the study
  • Patient affiliated to a social security scheme or benefiting from such a scheme

Exclusion

  • Viscosupplementation less than 6 months old
  • Intra-articular corticosteroid injection less than 2 months old
  • Inflammatory arthritis or active infectious of the knee studied
  • History of surgery of the lower limb concerned
  • Kellgren \& Lawrence grades not defined
  • Known hypersensitivity to hyaluronic acid or chondroitin sulfate
  • Pregnant or breastfeeding women
  • Patient under guardianship, curatorship or judicial safeguard
  • Patient participating in another clinical investigation, at the time of inclusion

Key Trial Info

Start Date :

February 7 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

August 1 2024

Estimated Enrollment :

134 Patients enrolled

Trial Details

Trial ID

NCT06087705

Start Date

February 7 2023

End Date

August 1 2024

Last Update

October 18 2023

Active Locations (1)

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1

CRRF en Milieu Marin de Trestel

Saint-Brieuc, France, 22000