Status:
UNKNOWN
Topical Pentoxifylline; Metformin Versus Betamethasone in the Treatment of Alopecia Areata.
Lead Sponsor:
Assiut University
Conditions:
Alopecia Areata
Eligibility:
All Genders
6-60 years
Phase:
PHASE1
Brief Summary
To compare the efficacy and safety of topical pentoxifylline 2% gel and topical metformin 10% gel versus topical betamethasone valerate 0.1% cream, in treatment of patchy alopecia areata.
Detailed Description
Alopecia areata (AA) is a common tissue-specific autoimmune disease characterized by non-scaring hairloss. Alopecia areata affects around 2.1% of the population at a point of their life. It affects b...
Eligibility Criteria
Inclusion
- A clinical diagnosis of patchy alopecia areata of scalp involving \< 50% of the total scalp confirmed by dermoscopy of both males and females.
- patients age between 6 and 60 years old.
Exclusion
- Alopecia totalis and alopecia universalis.
- Cicatricial alopecia.
- Other causes of hair loss such as; endocrine or immunological disease.
- Skin disease in the affected area.
- Hypersensitivity or allergy to any of the treatment products used.
- Patient using treatment (topical or systemic) for alopecia areata in the last 2 months.
- Systemic administration of any of the three test drugs (pentoxifylline, metformin and steroids).
- Pregnant and lactating females.
Key Trial Info
Start Date :
October 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2024
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06087796
Start Date
October 1 2023
End Date
October 1 2024
Last Update
October 18 2023
Active Locations (1)
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1
Assiut university
Asyut, Egypt, 71515