Status:
RECRUITING
Micro-expressions in Patients With Prolonged Disorders of Consciousness
Lead Sponsor:
First Affiliated Hospital of Zhejiang University
Conditions:
Consciousness Disorders
Eligibility:
All Genders
18-80 years
Brief Summary
The goal of this observational study is to learn about the microexpressions in patients with prolonged disorders of consciousness. The main questions it aims to answer are: * Inducing micro-expressio...
Detailed Description
In accordance with the inclusion and exclusion criteria, a total of about 200 participants will be recruited, including about 150 confirmed cases of prolonged disorders of consciousness and 50 healthy...
Eligibility Criteria
Inclusion
- Patients with consciousness disorders for more than 28 days following severe brain injury, assessed by the CRS-R scale to meet the criteria for VS or MCS;
- Aged between 18 and 80 years;
- Stable vital signs;
- Voluntary participation of family members with signed informed consent;
- Good cooperation, minimal facial and spontaneous activities, no use of antiepileptic or sedative drugs.
Exclusion
- Locked-in syndrome;
- Contraindications for EEG examination;
- Contraindications for MRI scanning, such as the presence of internal metallic implants;
- Diseases and factors that may affect brain function assessment, such as metabolic disorders, poisoning, shock, etc.
Key Trial Info
Start Date :
June 27 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT06088628
Start Date
June 27 2022
End Date
December 1 2026
Last Update
October 18 2023
Active Locations (1)
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1
First Affiliated Hospital,Zhejiang University
Hangzhou, Zhejiang, China, 310003