Status:
UNKNOWN
Nebulization Versus Spray-as-You-Go Airway Topical Anesthesia Using Dexmedetomidine and Lidocaine Mixture During Awake Flexible Fiberoptic Intubation in Temporomandibular Ankylosis
Lead Sponsor:
Tanta University
Conditions:
Nebulization
Spray-as-You-Go
Eligibility:
All Genders
21-65 years
Phase:
NA
Brief Summary
The aim of this study is to compare the efficacy of airway topical anesthesia with nebulization to the spray-as-you-go technique using dexmedetomidine and lidocaine mixture to achieve upper airway ane...
Detailed Description
Awake fiber-optic intubation (AFOI) has become the accepted gold standard technique for management of recognized difficult airway as the larynx remains in a posterior position and the patient is able ...
Eligibility Criteria
Inclusion
- Age from 21to 65 years.
- Both sexes.
- American Society of Anesthesiologists (ASA) physical status I or II and scheduled for elective surgery requiring general anesthesia , and known to have Temporomandibular joint ankylosis and expected to be difficult intubation patient due to restriction of jaw mobility and limited mouth opening less than 2 fingers.
Exclusion
- History of allergy to dexmedetomidine or lidocaine.
- History of drug abuse.
- Concomitant use of medications which may exaggerate the heart rate (HR) response of -dexmedetomidine (e.g. digoxin or β-adrenergic antagonists), HR \<50 beats/min, systolic blood pressure (SBP) \<90 mmHg.
- Pregnancy.
- Morbid obesity( BMI more than 35).
- Patients on anticoagulants, nasal trauma, deformity or polyp, CSF rhinorrhea, fracture base skull.
- Cardiac and/or respiratory disease, reactive airway disease, hepatic or renal disorders.
Key Trial Info
Start Date :
October 18 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2024
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT06088875
Start Date
October 18 2023
End Date
May 1 2024
Last Update
October 19 2023
Active Locations (1)
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1
Tanta University
Tanta, El-Gharbia, Egypt, 31527