Status:
UNKNOWN
High-risk Features of Coronary Lesions in CTA and OCT
Lead Sponsor:
Shanghai Zhongshan Hospital
Conditions:
Acute Coronary Syndromes
Eligibility:
All Genders
18+ years
Brief Summary
This study is a multicenter and retrospective study. ACS patients who underwent CCTA or OCT from 1 months to 3 years prior to the event will be retrospectively identified. Plaques in the non-culprit v...
Detailed Description
The high-risk features of plaque rupture and subsequent acute coronary syndrome (ACS) are not fully identified. Plaque features, hemodynamic forces, and the interaction between these factors may cause...
Eligibility Criteria
Inclusion
- Patients who presented with ACS and underwent invasive coronary angiography or OCT
- The patients who underwent coronary CT angiography, regardless of the reason (for example, routine healthcare check-up, or evaluation for stable angina or atypical chest pain) prior to the acute event.
- Time limit of CCTA: 1 months \~ 3 years prior to the event.
Exclusion
- Patients with stents in two or more vessel territories prior to CCTA Poor quality of CCTA which is unsuitable for plaque and CFD analysis Patients with ACS culprit lesion in a stented segment Patients with previous history of coronary artery bypass graft surgery Patients with revascularization after CCTA and before ACS event Secondary ACS due to other general medical conditions, such as sepsis, arrhythmia, bleeding, etc.
- -Additional exclusion criteria for Computational Fluid Dynamics Poor quality CCTA images unsuitable for CFD and plaque analysis No unprocessed CCTA data
Key Trial Info
Start Date :
October 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2024
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT06089343
Start Date
October 1 2023
End Date
October 1 2024
Last Update
October 18 2023
Active Locations (1)
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1
Zhongshan Hospital Fudan University
Shanghai, Shanghai Municipality, China, 200030