Status:

NOT_YET_RECRUITING

The Effect of Jiajian Guishen Granules on the Modulation of Ovarian Function in Patients With Poor Ovarian Response(POR)

Lead Sponsor:

Shi Yun

Collaborating Sponsors:

Capital Medical University

Conditions:

Poor Ovarian Response

Eligibility:

FEMALE

20-45 years

Phase:

EARLY_PHASE1

Brief Summary

Relying on the Department of Gynecology of Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine and chaoyang hospital of Capital medical university, this randomized controlled cli...

Detailed Description

This study was a multicenter, stratified block randomized, double-blind, double simulation, positive controlled clinical trial.

Eligibility Criteria

Inclusion

  • Woman who meet the diagnostic criteria for poor ovarian response;
  • Woman who meet the TCM diagnostic criteria for kidney deficiency;
  • Woman whose serum basal FSH(two consecutive menstrual cycles)between 10-25mIU/mL
  • Woman whose AMH \<1.1ng/ml;
  • Woman aged ranged from 20-45 years old
  • Woman whose body mass index (BMI)\<35 kg/m2
  • Womanwho voluntarily signed the informed consent form.

Exclusion

  • Woman who have combination of serious diseases such as cardiovascular, cerebrovascular, hepatic, renal and hematopoietic systems, and malignant tumors;
  • Woman who have other endocrine diseases, such as polycystic ovary syndrome and hyperprolactinemia;
  • Woman who are unable to cooperate with the treatment and follow-up, such as combined neurological and psychiatric disorders, or those who are unwilling to cooperate.
  • Woman who have used the same efficacy of herbs or other therapies in the last 1 month;
  • Woman who are allergic to the drugs used in this study.

Key Trial Info

Start Date :

June 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 31 2025

Estimated Enrollment :

76 Patients enrolled

Trial Details

Trial ID

NCT06089395

Start Date

June 1 2024

End Date

August 31 2025

Last Update

May 2 2024

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Dongzhimen Hospital of Beijing University of Chinese Medicine

Beijing, Beijing Municipality, China, 100700

2

Chaoyang Hospital Affiliated to Capital Medical University

Beijing, China