Status:

RECRUITING

Early vs Postponed Parenteral Nutrition After Emergency Abdominal Surgery

Lead Sponsor:

Copenhagen University Hospital at Herlev

Collaborating Sponsors:

Copenhagen University Hospital, Hvidovre

Nordsjaellands Hospital

Conditions:

Laparotomy

Bowel Obstruction

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

The aim of this study is to investigate the effect of early, supplementary parenteral nutrition following emergency laparotomy. Currently, parenteral nutrition is used in postoperative patients if or...

Detailed Description

Screening for potential participants will be done using the patient records which includes primary procedure, age, NRS-2002 score, and total calorie intake within the last 24 hours. Only information n...

Eligibility Criteria

Inclusion

  • Age \> 18
  • Emergency primary midline laparotomy or laparoscopy
  • NRS-2002 (nutritional risk screening) score \< 7
  • No contraindications for oral or enteral nutrition after surgery
  • Unable to tolerate or take in at least 50% of calculated calorie requirement on postoperative day 2
  • Capable of providing informed consent at the time of inclusion

Exclusion

  • Laparotomy without closure of the abdominal aponeurosis
  • Laparoscopic appendectomy or cholecystectomy as the procedure
  • Limiting mental or psychiatric disorders rendering participation unethical or unrealistic
  • Patients with a very limited expected remaining time of living (\< 3 months)
  • NRS-2002 = 7
  • Pregnant or breastfeeding women
  • Refusal to participate

Key Trial Info

Start Date :

October 18 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 1 2026

Estimated Enrollment :

342 Patients enrolled

Trial Details

Trial ID

NCT06089551

Start Date

October 18 2023

End Date

January 1 2026

Last Update

February 12 2025

Active Locations (1)

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1

Herlev Hospital

Herlev, Denmark, 2730