Status:

UNKNOWN

Liquid Biopsy for the Diagnosis of Intestinal-type Adenocarcinoma of the Ethmoid (BLADE)

Lead Sponsor:

University Hospital, Montpellier

Collaborating Sponsors:

GEFLUC Occitanie

Conditions:

Ethmoid Sinus Tumor

Adenocarcinoma

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The role of this transversal study is to assess the specificity and sensitivity of liquid biopsy to detect circulating cells tumor of adenocarcinoma of the ethmoid. Blood sample of participants will ...

Eligibility Criteria

Inclusion

  • Case group: diagnosis of adenocarcinoma of the ethmoid on biopsy or imaging recurence; age\>/= 18 years; patient consent ;
  • Age and gender-matched control group: consulting patient in otolaryngology head and neck surgery department without adenocarcinoma of the ethmoid; no personal history of cancer; no familial history of colorectal adenocarcinoma;
  • Exposition control group: Professional exposition to wood dust, leaver or nickel for at least 12 months; consulting patient in otolaryngology head and neck surgery department without adenocarcinoma of the ethmoid; no personal history of cancer; no familial history of colorectal adenocarcinoma;

Exclusion

  • patient presenting with another malignant tumor
  • deprivation of liberty
  • patient under guardianship
  • Other cancer diagnosed or under treatment
  • Recurrent patient previously included in the study
  • Refusal to accept the monitoring described and/or to provide the information required for the study
  • No affiliation or non-beneficiary of a Social Security system;
  • Pregnant or breast-feeding women in accordance with article L1121-5 of the Public Health Code (CSP)

Key Trial Info

Start Date :

December 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

42 Patients enrolled

Trial Details

Trial ID

NCT06090214

Start Date

December 1 2023

End Date

December 1 2025

Last Update

October 19 2023

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