Status:

COMPLETED

Is Sacubitril-valsartan Superior to Dapagliflozin in Improving Myocardial Function Performance

Lead Sponsor:

Ain Shams University

Conditions:

Heart Failure

Eligibility:

All Genders

50-70 years

Phase:

NA

Brief Summary

The aim of this study is to assess whether sacubitril-valsartan is more effective than dapagliflozin in improving function, myocardial performance in patients undergoing CABG operation or not

Detailed Description

Coronary revascularization has matured as a field since coronary artery bypass grafting (CABG) was first developed over 50 years ago, with diagnostic and treatment methods have advanced dramatically. ...

Eligibility Criteria

Inclusion

  • Age between 50 to 70 years old
  • DM type 2
  • ASA 3
  • Only 2 coronary grafts
  • Elective surgery
  • Bypass time less than 1 hour
  • Senior staff cardiothoracic

Exclusion

  • ASA 4 or more
  • Emergency surgery
  • Bypass time of more than 1 hour
  • Coronary grafts of more than 2
  • Any allergy to the used drugs

Key Trial Info

Start Date :

February 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2024

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT06090487

Start Date

February 1 2024

End Date

March 1 2024

Last Update

September 5 2024

Active Locations (1)

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1

Ain Shams University

Cairo, Egypt