Status:

COMPLETED

Cefixime Plus Doxycycline Compared to Ceftriaxone Plus Azithromycin for Treatment of Gonorrhoea

Lead Sponsor:

Bulovka Hospital

Collaborating Sponsors:

Örebro University, Sweden

Conditions:

Gonorrhea

Eligibility:

All Genders

18-65 years

Phase:

PHASE4

Brief Summary

A non-inferiority, open-label, multicentre randomised controlled trial to compare two therapeutic regimens for the treatment of uncomplicated urogenital, rectal or pharyngeal gonorrhoea in men and wom...

Detailed Description

Non-inferiority, open-label, multicentre randomised clinical trial (RCT) compared two regimens for the treatment of uncomplicated urogenital, rectal or pharyngeal gonorrhoea in men and women between 1...

Eligibility Criteria

Inclusion

  • uncomplicated urogenital, rectal or pharyngeal gonorrhoea diagnosed using the nucleic acid amplification test

Exclusion

  • any antimicrobial treatment during the 4 weeks before study enrolment
  • pregnancy or lactation
  • autoimmune disease
  • renal, hepatic or cardiac insufficiency
  • immunosuppressive therapy
  • allergy to cephalosporins, macrolides or doxycycline

Key Trial Info

Start Date :

April 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 22 2022

Estimated Enrollment :

161 Patients enrolled

Trial Details

Trial ID

NCT06090565

Start Date

April 1 2021

End Date

December 22 2022

Last Update

October 23 2023

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Venereology Prague, Medicentrum Beroun

Prague, Czechia, 15000

2

University Hospital Bulovka

Prague, Czechia, 18081