Status:
COMPLETED
Initial Volume Status in Patients With Acute Brain Injury is Associated With Neurological Prognosis
Lead Sponsor:
Peking Union Medical College Hospital
Conditions:
Acute Brain Injury
Paroxysmal Sympathetic Hyperactivity
Eligibility:
All Genders
18-85 years
Brief Summary
In this study, we investigated the clinical variability in paroxysmal sympathetic hyperactivity in patients with acute brain injury and examined the prognostic value of the Paroxysmal Sympathetic Hype...
Eligibility Criteria
Inclusion
- Only adult patients (\>18 years of age) were included. The other inclusion criteria were 1) definite cerebrovascular accident or craniocerebral injury (a clear change in consciousness or suggestive imaging); 2) the ability to undergo ultrasound to obtain information on volume status and cardiac and pulmonary monitoring; and 3) fulfilment of the measurement conditions.
Exclusion
- The exclusion criteria were 1) a history of cardiovascular disease, such as coronary artery disease, heart failure, or atrial fibrillation; 2) presence of severe valvular disease or an EF of \<30%; 3) chronic lung disease; 4) chronic liver failure or renal insufficiency; 5) comorbid malignant neoplasm or acute/chronic infectious disease prior to craniocerebral injury; 6) pregnancy or breastfeeding; 7) history of psychiatric disorders; 8) history of drug abuse or alcohol misuse; 9) history of β-blocker use; 10) comorbid spinal cord injury; 11) death or discharge from hospital within 5 days of hospitalization.
Key Trial Info
Start Date :
January 1 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 1 2022
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT06090812
Start Date
January 1 2021
End Date
January 1 2022
Last Update
April 1 2024
Active Locations (1)
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1
Wei Du
Beijing, Beijing Municipality, China, 100010