Status:

COMPLETED

Magnesium Sulfate in Surgical Stress Attenuation Postoperative Sore Throat and Stress Response Induced Tracheal Intubation

Lead Sponsor:

Assiut University

Conditions:

Anesthesia Complication

Anesthesia Intubation Complication

Eligibility:

All Genders

20-50 years

Phase:

NA

Brief Summary

Magnesium sulfate has many mechanisms of action for attenuating the stress response as inhibition of catecholamine releasing from the adrenal medulla, keeping the plasma concentration of epinephrine a...

Detailed Description

Inclusion criteria * 20-50 years old * ASA: 1, 2 * Elective fit laparoscopic cholecystectomy Exclusion criteria * Patient refusal * patients with history of hypersensitivity to magnesium sulphate * p...

Eligibility Criteria

Inclusion

  • 20-50 years old
  • ASA: 1, 2
  • Elective fit laparoscopic cholecystectomy

Exclusion

  • -Patient refusal
  • patients with history of hypersensitivity to magnesium sulphate
  • patients with coronary ischemic disease, atrioventricular block of any degree, known cardiac arrhythmias, heart failure
  • on beta blockers or calcium channel blockers
  • expected difficult intubation (Mallampati 4)
  • Body mass index \> 40

Key Trial Info

Start Date :

November 15 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 28 2025

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT06091631

Start Date

November 15 2023

End Date

February 28 2025

Last Update

December 22 2025

Active Locations (1)

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1

Assiut university, faculty of medicine, anesthesia and ICU and pain management department

Asyut, Asyut Governorate, Egypt, 71515