Status:
UNKNOWN
Quantitative Assessment of Lid Margin Vascularity Using SS-OCTA
Lead Sponsor:
Wenzhou Medical University
Conditions:
Ss-octa
Lid Margin Blood Flow Density
Eligibility:
All Genders
20+ years
Brief Summary
To explore an optimized scan technique for the detection of lid margin vasculature
Detailed Description
To investigate whether the SS-OCTA tool has the potential to characterize the lid margin vascularity in MGD patients. The repeatability and validity of OCTA in assessing eyelid margin blood flow densi...
Eligibility Criteria
Inclusion
- The MGD patients were aged \>\_20 years and were diagnosed according to Chinese MGD diagnostic criteria,11 including dry eye symptoms, and at least one of the following signs: (1) poor meibum expressibility or quality; (2) at least one of eyelid margin abnormalities (lid margin irregularity, plugging of the gland orifice, vascular engorgement/telangiectasia, and anterior replacement of the mucocutaneous junction. Normal subjects were defined as adults without any dry eye symptoms and lid margin abnormality.
Exclusion
- (1) subjects with ocular diseases or conditions known to affect the anatomy of the anterior segment, such as acute ocular inflammation, a history of eyelid surgery, contact lens wear within two weeks, and/or eyelid trauma; (2) subjects with of history of systemic or topical medications that might cause ocular congestion; (3) subjects with severe systemic illness or pregnancy; and (4) subjects who were difficult to cooperate with examination, resulting the obtained images were not sufficiently clear for automatic analysis.
Key Trial Info
Start Date :
October 20 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
February 28 2024
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT06091722
Start Date
October 20 2023
End Date
February 28 2024
Last Update
October 19 2023
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