Status:
UNKNOWN
Effectiveness of Botulinum Toxin in Freezing of Gate in Parkinson's Disease Walking in Parkinson's Disease.
Lead Sponsor:
Centro Hospitalar de Lisboa Central
Conditions:
Freezing of Gate
Parkinson Disease
Eligibility:
All Genders
Phase:
NA
Brief Summary
Freezing of gait is a symptom of Parkinson's disease (PD) that becomes more evident with the evolution of the disease, and which presents an important difference compared to the other signs and sympto...
Detailed Description
Study with therapeutic intervention, placebo-controlled, double-blind, with stratified randomization using the minimization method. The variables to consider by this method will be binary variables an...
Eligibility Criteria
Inclusion
- people with idiopathic Parkinson's disease with the presence of gait freezing, which scores \> 1 at point 2.13 of the MDS-UPDRS8 scale and is responsive to cueing techniques, with severity of Parkinson's disease classified between 3 and 4 on the Hoehn \& Yahr9 scale.
Exclusion
- previous exposure to toxin therapy, alteration of therapy for PD during the course of the study, cognitive impairment with MMSE10 \< 10.
Key Trial Info
Start Date :
June 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2025
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06094309
Start Date
June 1 2024
End Date
June 30 2025
Last Update
October 23 2023
Active Locations (1)
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1
Maria Margarida Grilo da Silva Dias
Lisbon, Portugal, 1150-199