Status:
RECRUITING
Cirrhotic Cardiomyopathy Based on Point-of-care Echocardiography, Biomarkers and Histology
Lead Sponsor:
Post Graduate Institute of Medical Education and Research, Chandigarh
Conditions:
Cirrhotic Cardiomyopathy
Cirrhosis, Liver
Eligibility:
All Genders
18-65 years
Brief Summary
Cirrhotic cardiomyopathy is associated with increased risk of complications like hepatorenal syndrome, refractory ascites, impaired response to stressors including sepsis, bleeding or transplantation,...
Detailed Description
The inability of the heart to cope with stress or sepsis induced circulatory failure is a key concept of the increased mortality risk due to LVDD. In view of the metabolic syndrome and diabetes epidem...
Eligibility Criteria
Inclusion
- Patients with cirrhosis who have been diagnosed by clinical, biochemical, histological (when available) criteria plus ultrasound imaging will be included if they meet the following:
- Age range of 18-65 years
- Cirrhosis with critical illness admitted to the Liver Intensive Care Unit
Exclusion
- Age \>65 years
- Chronic renal disease
- Pregnancy and peripartum cardiomyopathy
- Valvular heart disease
- Sick sinus syndrome/ Pacemaker
- Transjugular intrahepatic porto systemic shunt (TIPS) insertion
- Hepatocellular carcinoma
- Anemia Hb \< 8gm/dl in females, and \< 9 gm/dl in males at the time of assessment
Key Trial Info
Start Date :
July 15 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 15 2026
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT06095466
Start Date
July 15 2023
End Date
October 15 2026
Last Update
October 23 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Dr. Madhumita Premkumar
Sector-12, Chandigarh, India, 160012