Status:
RECRUITING
CAPACITY (Cardiac Amyloidosis and Physical ACtivITY) Study
Lead Sponsor:
Wake Forest University Health Sciences
Conditions:
Cardiac Amyloidosis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Exercise training in patients with heart failure and preserved ejection fraction (HFpEF) has been associated with an improvement in cardiorespiratory fitness and quality of life.
Detailed Description
The Atrium Health cardiac rehabilitation program delivers a comprehensive approach to improve cardiac performance including supervised exercise programs and has the ideal infrastructure to offer cardi...
Eligibility Criteria
Inclusion
- Age \> 18
- New York Heart Association (NYHA) Class I-III Heart Failure
- Able to Exercise
- On stable treatment for their cardiac amyloidosis or under active surveillance
- Life expectancy of at least 6 months
- Ability to understand and the willingness to sign a written informed consent document in English, and the willingness/ability to comply with the protocol activities
- Participant must be able and willing to follow the cardiac rehabilitation activities
Exclusion
- Inability to provide informed consent
- Inability to commit to in-person supervised exercise sessions for three one-hour sessions a week for 12 weeks
- NYHA Class IV Heart Failure
- Pulmonary disease requiring home oxygen
- Gait instability or history of prior falls
- In the opinion of the Principal Investigator, have a clinically significant comorbid disease that is likely to affect the ability of the patient to complete the trial, interfere with their ability with measurement of self-reported outcomes.
Key Trial Info
Start Date :
January 22 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2027
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT06096675
Start Date
January 22 2024
End Date
June 1 2027
Last Update
July 28 2025
Active Locations (1)
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1
Sanger Heart and Vascular Institute
Charlotte, North Carolina, United States, 28204