Status:

RECRUITING

Discovering New Targets for Colorectal and Endometrial Cancer Risk Reduction

Lead Sponsor:

Weill Medical College of Cornell University

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Colorectal Cancer

Endometrial Cancer

Eligibility:

All Genders

18+ years

Brief Summary

The primary aim of this study is to collect and store data, tissue, and personal and family histories from patients being screened for colorectal cancer and/or endometrial cancer at NYPH and WCM for r...

Detailed Description

Colorectal cancer (CRC) and endometrial cancer (EC) have a highly heritable component. Approximately 25% of CRC or EC patients have another first or second degree relative who are also affected by CRC...

Eligibility Criteria

Inclusion

  • The following eligibility criteria must be met as follows:
  • Age ≥ 18 years old.
  • One of the following must be met:
  • Diagnosis of a Hereditary Cancer Syndrome by positive genetic testing and/or clinical criteria to undergo an endoscopy procedure (esophagoduodenoscopy and/or colonoscopy/flexible sigmoidoscopy), or endometrial screening procedure (transvaginal ultrasound and/or hysteroscopy and/or endometrial biopsy), OR
  • Individuals coming to Weill-Cornell Medicine/NYPH to undergo an endoscopy procedure, transvaginal ultrasound, or hysteroscopy for average-risk (population-based) recommendation OR
  • Individuals diagnosed with colorectal cancer or endometrial cancer coming to Weill- Cornell Medicine/NYPH for surgical treatment OR
  • Individuals coming to Weill-Cornell Medicine/NYPH for care such as, but not limited to, diagnostic testing, clinic and/or treatment visit.
  • Willingness and ability to sign informed consent.
  • Ability to read/understand English, Spanish, and/or simplified Chinese.

Exclusion

    Key Trial Info

    Start Date :

    May 29 2019

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    December 31 2026

    Estimated Enrollment :

    1120 Patients enrolled

    Trial Details

    Trial ID

    NCT06096688

    Start Date

    May 29 2019

    End Date

    December 31 2026

    Last Update

    September 4 2025

    Active Locations (1)

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    NYP/Weill Cornell Medicine

    New York, New York, United States, 10065